​野間口研究室

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2021

Fundamental Virology: Curiosity-Oriented Basic Virus Research

Nomaguchi M.

Front. Virol. 2021 Dec 1;1:808768. doi: 10.3389/fviro.2021.808768

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The Expression Level of HIV-1 Vif Is Optimized by Nucleotide Changes in the Genomic SA1D2prox Region during the Viral Adaptation Process.

Koma T, Doi N, Takemoto M, Watanabe K, Yamamoto H, Nakashima S, Adachi A, Nomaguchi M. Viruses. 2021 Oct 15;13(10):2079. doi: 10.3390/v13102079.

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Special Issue "Cell, Organoid and Animal Models to Study Pathogenic Human RNA Viruses".

Adachi A, Nomaguchi M. Viruses. 2021 Sep 28;13(10):1943. doi: 10.3390/v13101943.

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Inactivation of SARS-CoV-2 by deep ultraviolet light emitting diode: A review.

Minamikawa T, Koma T, Suzuki A, Nagamatsu K, Yasui T, Yasutomo K, Nomaguchi M. Japanese Journal of Applied Physics 2021; 60: 090501. doi: 10.35848/1347-4065/ac19d1

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Species-specific valid ternary interactions of HIV-1 Env-gp120, CD4, and CCR5 as revealed by an adaptive single-amino acid substitution at the V3 loop tip.

Koma T, Yokoyama M, Kotani O, Doi N, Nakanishi N, Okubo H, Adachi S, Adachi A, Sato H, Nomaguchi M.

J Virol. 2021 Apr 21:JVI.02177-20. doi: 10.1128/JVI.02177-20. Online ahead of print.

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Immunological Responses to Seoul Orthohantavirus in Experimentally and Naturally Infected Brown Rats (Rattus norvegicus).

Yasuda SP, Shimizu K, Koma T, Hoa NT, Le MQ, Wei Z, Muthusinghe DS, Lokupathirage SMW, Hasebe F, Yamashiro T, Arikawa J, Yoshimatsu K. Viruses. 2021 Apr 12;13(4):665. doi: 10.3390/v13040665.

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Frontiers in Virology: An Innovative Platform for Integrative Virus Research.

Adachi A.

Front Virol. 2021 Mar 25;1:665473. doi: 10.3389/fviro.2021.665473.

 

Quantitative evaluation of SARS-CoV-2 inactivation using a deep ultraviolet light-emitting diode.

Minamikawa T, Koma T, Suzuki A, Mizuno T, Nagamatsu K, Arimochi H, Tsuchiya K, Matsuoka K, Yasui T, Yasutomo K, Nomaguchi M.

Sci Rep. 2021 Mar 3;11(1):5070. doi: 10.1038/s41598-021-84592-0.

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Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity.

Koma T, Huang C, Coscia A, Hallam S, Manning JT, Maruyama J, Walker AG, Miller M, Smith JN, Patterson M, Abraham J, Paessler S.

PLoS Pathog. 2021 Mar 1;17(3):e1009356. doi: 10.1371/journal.ppat.1009356. Online ahead of print.

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2020

Toward Understanding Molecular Bases for Biological Diversification of Human Coronaviruses: Present Status and Future Perspectives.

Koma T, Adachi S, Doi N, Adachi A, Nomaguchi M.

Front Microbiol. 2020 Aug 25;11:2016. doi: 10.3389/fmicb.2020.02016. eCollection 2020.

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Commentary: Derivation of Simian Tropic HIV-1 Infectious Clone Reveals Virus Adaptation to a New Host.

Adachi A, Koma T, Doi N, Nomaguchi M.

Front Cell Infect Microbiol. 2020 May 15;10:235. doi: 10.3389/fcimb.2020.00235. eCollection 2020.

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Commentary: Origin and evolution of pathogenic coronaviruses.

Adachi S, Koma T, Doi N, Nomaguchi M, Adachi A.

Front Immunol. 2020 Apr 21;11:811. doi: 10.3389/fimmu.2020.00811. eCollection 2020.

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Grand Challenge in Human/Animal Virology: Unseen, Smallest Replicative Entities Shape the Whole Globe.

Adachi A.

Front Microbiol. 2020 Mar 18;11:431. doi: 10.3389/fmicb.2020.00431. eCollection 2020

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The glycoprotein of the live-attenuated Junin virus vaccine strain induces ER stress and forms aggregates prior to degradation in the lysosome.

Manning JT, Yun NE, Seregin AV, Koma T, Sattler R, Ezeomah C, Huang C, de la Torre JC, Paessler S.

J Virol. 2020 Jan 29. pii: JVI.01693-19. doi: 10.1128/JVI.01693-19.

 

2019

Expression Level of HIV-1 Vif Can Be Fluctuated by Natural Nucleotide Variations in the vif-Coding and Regulatory SA1D2prox Sequences of the Proviral Genome.

Doi N, Koma T, Adachi A, Nomaguchi M.

Front Microbiol. 2019 Nov 28;10:2758. doi: 10.3389/fmicb.2019.02758. eCollection 2019.

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Role for Gag-CA Interdomain Linker in Primate Lentiviral Replication.

Doi N, Koma T, Adachi A, Nomaguchi M.

Front Microbiol. 2019 Aug 7;10:1831. doi: 10.3389/fmicb.2019.01831. eCollection 2019.

 

Allosteric regulation of HIV-1 capsid structure for Gag assembly, virion production, and viral infectivity by a disordered interdomain linker.

Koma T, Kotani O, Miyakawa K, Ryo A, Yokoyama M, Doi N, Adachi A, Sato H, Nomaguchi M.

J Virol. 2019 Jun 12. pii: JVI.00381-19. doi: 10.1128/JVI.00381-19.

 

PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.

Miyakawa K, Matsunaga S, Yokoyama M, Nomaguchi M, Kimura Y, Nishi M, Kimura H, Sato H, Hirano H, Tamura T, Akari H, Miura T, Adachi A, Sawasaki T, Yamamoto N, Ryo A.

Nat Commun. 2019 Apr 23;10(1):1844. doi: 10.1038/s41467-019-09867-7.

 

Concomitant Enhancement of HIV-1 Replication Potential and Neutralization-Resistance in Concert With Three Adaptive Mutations in Env V1/C2/C4 Domains.

Doi N, Yokoyama M, Koma T, Kotani O, Sato H, Adachi A, Nomaguchi M.

Front Microbiol. 2019 Jan 17;10:2. doi: 10.3389/fmicb.2019.00002. eCollection 2019.

 

2018

HIV-1 mutates to adapt in fluxing environments.

Nomaguchi M, Doi N, Koma T, Adachi A.

Microbes Infect. 2018 Oct - Nov;20(9-10):610-614. doi: 10.1016/j.micinf.2017.08.003.

 

CXCR4- and CCR5-Tropic HIV-1 Clones Are Both Tractable to Grow in Rhesus Macaques.

Doi N, Miura T, Mori H, Sakawaki H, Koma T, Adachi A, Nomaguchi M.

Front Microbiol. 2018 Oct 18;9:2510. doi: 10.3389/fmicb.2018.02510. eCollection 2018.

 

Review of Mammarenavirus Biology and Replication.

Hallam SJ, Koma T, Maruyama J, Paessler S.

Front Microbiol. 2018 Aug 3;9:1751. doi: 10.3389/fmicb.2018.01751. eCollection 2018.

 

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.

Clark LE, Mahmutovic S, Raymond DD, Dilanyan T, Koma T, Manning JT, Shankar S, Levis SC, Briggiler AM, Enria DA, Wucherpfennig KW, Paessler S, Abraham J.

Nat Commun. 2018 May 14;9(1):1884. doi: 10.1038/s41467-018-04271-z.

 

Zika virus infection elicits auto-antibodies to C1q.

Koma T, Veljkovic V, Anderson DE, Wang LF, Rossi SL, Shan C, Shi PY, Beasley DW, Bukreyeva N, Smith JN, Hallam S, Huang C, von Messling V, Paessler S.

Sci Rep. 2018 Jan 30;8(1):1882. doi: 10.1038/s41598-018-20185-8.

 

Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens.

Tong X, Smith J, Bukreyeva N, Koma T, Manning JT, Kalkeri R, Kwong AD, Paessler S.

Antiviral Res. 2018 Jan;149:34-40. doi: 10.1016/j.antiviral.2017.11.004. Epub 2017 Nov 8.

 

Virological characterization of HIV-1 CA-NTD mutants constructed in a virus-lineage reflected manner.

Nakanishi S, Watanabe S, Doi N, Koma T, Adachi A, Nomaguchi M.

J Med Invest. 2018;65(1.2):110-115. doi: 10.2152/jmi.65.110.

 

2017

Production of HIV-1 vif mRNA Is Modulated by Natural Nucleotide Variations and SLSA1 RNA Structure in SA1D2prox Genomic Region.

Nomaguchi M, Doi N, Yoshida T, Koma T, Adachi S, Ode H, Iwatani Y, Yokoyama M, Sato H, Adachi A.

Front Microbiol. 2017 Dec 18;8:2542. doi: 10.3389/fmicb.2017.02542. eCollection 2017.

 

Editorial: Highly Mutable Animal RNA Viruses: Adaptation and Evolution.

Nomaguchi M, Adachi A.

Front Microbiol. 2017 Sep 15;8:1785. doi: 10.3389/fmicb.2017.01785. eCollection 2017.

 

Complete Genome Sequences of Human Immunodeficiency Type 1 Viruses Genetically Engineered To Be Tropic for Rhesus Macaques.

Nomaguchi M, Doi N, Koma T, Adachi A.

Genome Announc. 2017 Sep 28;5(39). pii: e01063-17. doi: 10.1128/genomeA.01063-17.

 

Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells.

Huang C, Kolokoltsova OA, Mateer EJ, Koma T, Paessler S.

J Virol. 2017 Sep 27;91(20). pii: e01090-17. doi: 10.1128/JVI.01090-17. Print 2017 Oct 15.

 

Generation and characterization of new CCR5-tropic HIV-1rmt clones.

Doi N, Sakai Y, Adachi A, Nomaguchi M.

J Med Invest. 2017;64(3.4):272-279. doi: 10.2152/jmi.64.272.

 

Novel In Vitro Screening System Based on Differential Scanning Fluorimetry to Search for Small Molecules against the Disassembly or Assembly of HIV-1 Capsid Protein.

Miyazaki, Y., Doi, N., Koma, T., Adachi, A., and Nomaguchi, M.

Front Microbiol. 2017 Jul 24;8:1413. doi: 10.3389/fmicb.2017.01413. eCollection 2017.

 

Comparison of Biochemical Properties of HIV-1 and HIV-2 Capsid Proteins.

Miyazaki Y, Miyake A, Doi N, Koma T, Uchiyama T, Adachi A, Nomaguchi M.

Front Microbiol. 2017 Jun 13;8:1082. doi: 10.3389/fmicb.2017.01082. eCollection 2017.

 

2016

Phylogenetic Insights into the Functional Relationship between Primate Lentiviral Reverse Transcriptase and Accessory Proteins Vpx/Vpr.

Sakai Y, Doi N, Miyazaki Y, Adachi A, Nomaguchi M.

Front Microbiol. 2016 Oct 18;7:1655. eCollection 2016.

 

Expression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral Lineage.

Sakai Y, Miyake A, Doi N, Sasada H, Miyazaki Y, Adachi A, Nomaguchi M.

Front Microbiol. 2016 Aug 3;7:1211. doi: 10.3389/fmicb.2016.01211. eCollection 2016.

 

Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels.

Nomaguchi M, Doi N, Sakai Y, Ode H, Iwatani Y, Ueno T, Matsumoto Y, Miyazaki Y, Masuda T, Adachi A.

J Virol. 2016 Apr 14;90(9):4563-78. doi: 10.1128/JVI.02939-15. Print 2016 May.

 

Novel mutant human immunodeficiency virus type 1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random mutagenesis.

Sultana T, Nakayama EE, Tobita S, Yokoyama M, Seki Y, Saito A, Nomaguchi M, Adachi A, Akari H, Sato H, Shioda T.

J Gen Virol. 2016 Apr;97(4):963-76. doi: 10.1099/jgv.0.000408. Epub 2016 Jan 20.

 

In silico Analysis of HIV-1 Env-gp120 Reveals Structural Bases for Viral Adaptation in Growth-Restrictive Cells.

Yokoyama M, Nomaguchi M, Doi N, Kanda T, Adachi A, Sato H.

Front Microbiol. 2016 Feb 9;7:110. doi: 10.3389/fmicb.2016.00110. eCollection 2016.

 

2015

Single-amino acid mutation 66SR in Gag-matrix enhances viral single-cycle infectivity of R5-tropic HIV-1rmt.

Doi N, Sakai Y, Miyazaki Y, Adachi A, Nomaguchi M.

J Med Invest. 2015;62(3-4):228-32. doi: 10.2152/jmi.62.228.

 

2014

Animal model studies on viral infections.

Adachi A, Miura T.

Front Microbiol. 2014 Dec 3;5:672. doi: 10.3389/fmicb.2014.00672.

 

Distinct combinations of amino acid substitutions in N-terminal domain of Gag-capsid afford HIV-1 resistance to rhesus TRIM5α.

Nomaguchi M, Nakayama EE, Yokoyama M, Doi N, Igarashi T, Shioda T, Sato H, Adachi A.

Microbes Infect. 2014 Nov;16(11):936-44. doi: 10.1016/j.micinf.2014.08.017. Epub 2014 Sep 4.

 

Virological characterization of HIV-2 vpx gene mutants in various cell systems.

Nomaguchi M, Doi N, Adachi A.

Microbes Infect. 2014 Aug;16(8):695-701. doi: 10.1016/j.micinf.2014.06.004. Epub 2014 Jun 21.

 

Natural single-nucleotide polymorphisms in the 3' region of the HIV-1 pol gene modulate viral replication ability.

Nomaguchi M, Miyake A, Doi N, Fujiwara S, Miyazaki Y, Tsunetsugu-Yokota Y, Yokoyama M, Sato H, Masuda T, Adachi A.

J Virol. 2014 Apr;88(8):4145-60. doi: 10.1128/JVI.01859-13. Epub 2014 Jan 29.

 

Role of poly-proline motif in HIV-2 Vpx expression.

Miyake A, Miyazaki Y, Fujita M, Nomaguchi M, Adachi A.

Front Microbiol. 2014 Jan 28;5:24. doi: 10.3389/fmicb.2014.00024. eCollection 2014.

 

Poly-proline motif in HIV-2 Vpx is critical for its efficient translation.

Miyake A, Fujita M, Fujino H, Koga R, Kawamura S, Otsuka M, Ode H, Iwatani Y, Sakai Y, Doi N, Nomaguchi M, Adachi A, Miyazaki Y.

J Gen Virol. 2014 Jan;95(Pt 1):179-89. doi: 10.1099/vir.0.057364-0. Epub 2013 Oct 10.

 

Growth properties of macaque-tropic HIV-1 clones carrying vpr/vpx genes derived from simian immunodeficiency viruses in place of their vpr regions.

Doi N, Adachi A, Nomaguchi M.

J Med Invest. 2014;61(3-4):374-9.

 

2013

Generation of rhesus macaque-tropic HIV-1 clones that are resistant to major anti-HIV-1 restriction factors.

Nomaguchi M, Yokoyama M, Kono K, Nakayama EE, Shioda T, Doi N, Fujiwara S, Saito A, Akari H, Miyakawa K, Ryo A, Ode H, Iwatani Y, Miura T, Igarashi T, Sato H, Adachi A.

J Virol. 2013 Nov;87(21):11447-61. doi: 10.1128/JVI.01549-13. Epub 2013 Aug 21.

 

Growth potentials of CCR5-tropic/CXCR4-tropic HIV-1mt clones in macaque cells.

Doi N, Okubo A, Yamane M, Sakai Y, Adachi A, Nomaguchi M.

Front Microbiol. 2013 Jul 29;4:218. doi: 10.3389/fmicb.2013.00218. eCollection 2013.

 

TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1.

Saito A, Nomaguchi M, Kono K, Iwatani Y, Yokoyama M, Yasutomi Y, Sato H, Shioda T, Sugiura W, Matano T, Adachi A, Nakayama EE, Akari H.

J Gen Virol. 2013 Jun;94(Pt 6):1318-24. doi: 10.1099/vir.0.050252-0. Epub 2013 Mar 13.

 

Systemic biological analysis of the mutations in two distinct HIV-1mt genomes occurred during replication in macaque cells.

Nomaguchi M, Doi N, Fujiwara S, Saito A, Akari H, Nakayama EE, Shioda T, Yokoyama M, Sato H, Adachi A.

Microbes Infect. 2013 Apr;15(4):319-28. doi: 10.1016/j.micinf.2013.01.005. Epub 2013 Feb 4.

 

Gag-CA Q110D mutation elicits TRIM5-independent enhancement of HIV-1mt replication in macaque cells.

Nomaguchi M, Yokoyama M, Kono K, Nakayama EE, Shioda T, Saito A, Akari H, Yasutomi Y, Matano T, Sato H, Adachi A.

Microbes Infect. 2013 Jan;15(1):56-65. doi: 10.1016/j.micinf.2012.10.013. Epub 2012 Nov 1.

 

2012

Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu.

Miyakawa K, Sawasaki T, Matsunaga S, Tokarev A, Quinn G, Kimura H, Nomaguchi M, Adachi A, Yamamoto N, Guatelli J, Ryo A.

Sci Signal. 2012 Oct 9;5(245):ra73. doi: 10.1126/scisignal.2003212.

 

SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein.

Fujita M, Nomaguchi M, Adachi A, Otsuka M.

Front Microbiol. 2012 Aug 10;3:297. doi: 10.3389/fmicb.2012.00297. eCollection 2012.

 

Viral tropism.

Nomaguchi M, Fujita M, Miyazaki Y, Adachi A.

Front Microbiol. 2012 Aug 3;3:281. doi: 10.3389/fmicb.2012.00281. eCollection 2012.

 

Species tropism of HIV-1 modulated by viral accessory proteins.

Nomaguchi M, Doi N, Matsumoto Y, Sakai Y, Fujiwara S, Adachi A.

Front Microbiol. 2012 Jul 26;3:267. doi: 10.3389/fmicb.2012.00267. eCollection 2012.

 

Structural biology for virus research.

Miyazaki Y, Fujita M, Nomaguchi M, Adachi A.

Front Microbiol. 2012 Mar 13;3:91. doi: 10.3389/fmicb.2012.00091. eCollection 2012.

 

Geographical, genetic and functional diversity of antiretroviral host factor TRIMCyp in cynomolgus macaque (Macaca fascicularis).

Saito A, Kono K, Nomaguchi M, Yasutomi Y, Adachi A, Shioda T, Akari H, Nakayama EE.

J Gen Virol. 2012 Mar;93(Pt 3):594-602. doi: 10.1099/vir.0.038075-0. Epub 2011 Nov 23.

 

2011

Structural dynamics of retroviral genome and the packaging.

Miyazaki Y, Miyake A, Nomaguchi M, Adachi A.

Front Microbiol. 2011 Dec 29;2:264. doi: 10.3389/fmicb.2011.00264. eCollection 2011.

 

Commentary on a New Era of Investigating 3D Structure-Based Human-Virus Protein Network Dynamics.

Adachi S, Adachi A, Nomaguchi M.

Front Microbiol. 2011 Sep 8;2:186. doi: 10.3389/fmicb.2011.00186. eCollection 2011.

 

The Fourth Major Restriction Factor Against HIV/SIV.

Nomaguchi M, Fujita M, Adachi A.

Front Microbiol. 2011 Jun 10;2:132. doi: 10.3389/fmicb.2011.00132. eCollection 2011.

 

Rhesus M1.3S Cells Suitable for Biological Evaluation of Macaque-Tropic HIV/SIV Clones.

Doi N, Fujiwara S, Adachi A, Nomaguchi M.

Front Microbiol. 2011 May 23;2:115. doi: 10.3389/fmicb.2011.00115. eCollection 2011.

 

HIV-1 Vpr and G2 cell cycle arrest.

Nomaguchi M, Adachi A.

Future Microbiol. 2011 Apr;6(4):375-8. doi: 10.2217/fmb.11.17.

 

Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications.

Saito A, Nomaguchi M, Iijima S, Kuroishi A, Yoshida T, Lee YJ, Hayakawa T, Kono K, Nakayama EE, Shioda T, Yasutomi Y, Adachi A, Matano T, Akari H.

Microbes Infect. 2011 Jan;13(1):58-64. doi: 10.1016/j.micinf.2010.10.001. Epub 2010 Oct 16.

 

2010

Site-Directed Mutagenesis of HIV-1 vpu Gene Demonstrates Two Clusters of Replication-Defective Mutants with Distinct Ability to Down-Modulate Cell Surface CD4 and Tetherin.

Nomaguchi M, Doi N, Fujiwara S, Fujita M, Adachi A.

Front Microbiol. 2010 Nov 24;1:116. doi: 10.3389/fmicb.2010.00116. eCollection 2010.

 

Growth ability in various macaque cell lines of HIV-1 with simian cell-tropism.

Doi N, Fujiwara S, Adachi A, Nomaguchi M.

J Med Invest. 2010 Aug;57(3-4):284-92.

 

[HIV infection].

Nomaguchi M, Adachi A.

Nihon Rinsho. 2010 Aug;68 Suppl 8:518-22. Review. Japanese.

 

Virology as biosystematics: towards understanding the viral infection biology.

Nomaguchi M, Adachi A.

Front Microbiol. 2010 Jul 20;1:2. doi: 10.3389/fmicb.2010.00002. eCollection 2010.

 

Multifaceted activity of HIV Vpr/Vpx proteins: the current view of their virological functions.

Fujita M, Otsuka M, Nomaguchi M, Adachi A.

Rev Med Virol. 2010 Mar;20(2):68-76. doi: 10.1002/rmv.636. Review.

 

Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F.

Nagao T, Yamashita T, Miyake A, Uchiyama T, Nomaguchi M, Adachi A.

J Med Invest. 2010 Feb;57(1-2):89-94.

 

Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.

Yamashita T, Nomaguchi M, Miyake A, Uchiyama T, Adachi A.

Microbes Infect. 2010 Feb;12(2):166-71. doi: 10.1016/j.micinf.2009.11.007. Epub 2009 Nov 26.

 

Role of HIV-1 Nef protein for virus replication in vitro.

Jere A, Fujita M, Adachi A, Nomaguchi M.

Microbes Infect. 2010 Jan;12(1):65-70. doi: 10.1016/j.micinf.2009.09.009. Epub 2009 Sep 19. Review.

 

2009

Modification of a loop sequence between alpha-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) vif and CA alpha-helices 4 and 5 loop improves replication in cynomolgus monkey cells.

Kuroishi A, Saito A, Shingai Y, Shioda T, Nomaguchi M, Adachi A, Akari H, Nakayama EE.

Retrovirology. 2009 Aug 3;6:70. doi: 10.1186/1742-4690-6-70.

 

[Accessory proteins of HIV and innate anti-retroviral factors].

Nomaguchi M, Adachi A.

Uirusu. 2009 Jun;59(1):67-74. Review. Japanese.

 

Amino acid alterations in Gag that confer the ability to grow in simian cells on HIV-1 are located at a narrow CA region.

Nagao T, Hatcho K, Doi N, Fujiwara S, Adachi A, Nomaguchi M.

J Med Invest. 2009 Feb;56(1-2):21-5.

 

Evasion from CypA- and APOBEC-mediated restrictions is insufficient for HIV-1 to efficiently grow in simian cells.

Kamada K, Yamashita T, Hatcho K, Adachi A, Nomaguchi M.

Microbes Infect. 2009 Feb;11(2):164-71. doi: 10.1016/j.micinf.2008.11.002. Epub 2008 Nov 19.

 

2008

Functional region mapping of HIV-2 Vpx protein.

Fujita M, Otsuka M, Nomaguchi M, Adachi A.

Microbes Infect. 2008 Oct;10(12-13):1387-92. doi: 10.1016/j.micinf.2008.08.005. Epub 2008 Aug 14.

 

Growth ability in simian cells of monkey cell-tropic HIV-1 is greatly affected by downstream region of the vif gene.

Yamashita T, Doi N, Adachi A, Nomaguchi M.

J Med Invest. 2008 Aug;55(3-4):236-40.

 

Vpx is critical for reverse transcription of the human immunodeficiency virus type 2 genome in macrophages.

Fujita M, Otsuka M, Miyoshi M, Khamsri B, Nomaguchi M, Adachi A.

J Virol. 2008 Aug;82(15):7752-6. doi: 10.1128/JVI.01003-07. Epub 2008 May 21.

 

Replication potentials of vif variant viruses generated from monkey cell-tropic HIV-1 derivative clones NL-DT5/NL-DT5R.

Hatcho K, Kamada K, Yamashita T, Adachi A, Nomaguchi M.

Microbes Infect. 2008 Aug-Sep;10(10-11):1218-22. doi: 10.1016/j.micinf.2008.06.007. Epub 2008 Jun 20.

 

Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F.

Yamashita T, Kamada K, Hatcho K, Adachi A, Nomaguchi M.

Microbes Infect. 2008 Aug-Sep;10(10-11):1142-9. doi: 10.1016/j.micinf.2008.06.003. Epub 2008 Jun 18.

 

Role of HIV-1 Vpu protein for virus spread and pathogenesis.

Nomaguchi M, Fujita M, Adachi A.

Microbes Infect. 2008 Jul;10(9):960-7. doi: 10.1016/j.micinf.2008.07.006. Epub 2008 Jul 10. Review.

 

Species barrier of HIV-1 and its jumping by virus engineering.

Nomaguchi M, Doi N, Kamada K, Adachi A.

Rev Med Virol. 2008 Jul-Aug;18(4):261-75. doi: 10.1002/rmv.576. Review.

 

Specific requirements for elements of the 5' and 3' terminal regions in flavivirus RNA synthesis and viral replication.

Yu L, Nomaguchi M, Padmanabhan R, Markoff L.

Virology. 2008 Apr 25;374(1):170-85. doi: 10.1016/j.virol.2007.12.035. Epub 2008 Jan 29.

 

2007

[Functional roles of HIV-1 accessory genes for its pathogenicity].

Adachi A, Kamada K, Hatcho K, Yamashita T, Uchiyama T, Nomaguchi M.

Tanpakushitsu Kakusan Koso. 2007 Aug;52(10 Suppl):1261-7. Review. Japanese.